Syndrome of polyneuropathy, skin hyperpigmentation, oedema and hepatosplenomegaly.
نویسندگان
چکیده
منابع مشابه
Plasma cell dyscrasia with polyneuritis and dermato-endocrine alterations. Report of a new case outside Japan.
A new syndrome has been described comprising polyneuropathy, oedema, hyperpigmentation and thickening of the skin, gynaecomastia in males and amenorrhoea in females, monoclonal gammopathy, papilloedema and diabetes. There is frequent osteosclerosis with or without plasmacytoma, hepatosplenomegaly and polycythaemia. There is a good response to corticosteroids, immunosuppressive drugs and occasio...
متن کاملPolyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome.
A patient with a three year history of POEMS syndrome-polyneuropathy, hepatosplenomegaly M-protein, skin changes, optic disc edema, peripheral oedema, pleuritis, lymphadenopathy, and osteosclerotic myeloma is described. The patient had a twenty year history of psoriasis and impotence was the first sign of the disease. The pathophysiology of this multisystem disorder is unknown, although the M-p...
متن کاملTigecycline Induced Hyperpigmentation of the Skin
A 65-year old patient developed a sacral decubitus ulcer with osteomyelitis after a jaw reconstruction for osteonecrosis of the jaw. (Figure 1B illustrates the skin color just before start of tigecycline treatment). Based on cultures, the unfavourable evolution of the wounds, and her β-lactam allergy, tigecycline was given for a total of 102 days. After 2.5 months of treatment, a progressive br...
متن کاملPemetrexed-induced hyperpigmentation of the skin.
Pemetrexed (Alimta™) is used frequently for the treatment of lung cancer and is associated with various types and grades of cutaneous side-effects. We report here one patient who presented with asymptomatic hyperpigmentation of the skin, localized on the palms of the hands and the soles of the feet after administration of pemetrexed for lung cancer despite receiving standard pre-medication. Thi...
متن کاملگزارش یک مورد نشانگان پوئمز (POEMS SYNDROME) از ایران و مروری بر مقالاتی که در این زمینه منتشر شده است.
The crow-fukas, Takatsuki or POEMS syndrome (The acronym of Polyneuropathy, Organomegaly, endocrinopathy, M component and skin changes), a rare, multisystem disorder associated with osteosclerotic myeloma, is characterize by the combination of plasma cell discrasia with polyneuropathy, organomegaly, endocrinopathy, monoclonal(M) protein, skin changes, as well as various other sign, such...
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ژورنال
عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry
سال: 1983
ISSN: 0022-3050
DOI: 10.1136/jnnp.46.12.1108